Zentalis Pharmaceuticals

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Description

Zentalis Pharmaceuticals is a clinical-stage biopharmaceutical company focused on discovering and developing small molecule therapeutics targeting fundamental biological pathways of cancers.

The Company's products include ZN-c5 and ZN-c3. ZN-c5 is an oral selective estrogen receptor degrader, which is in a Phase I/II clinical trial for the treatment of advanced estrogen receptor-positive, human epidermal growth factor receptor 2-negative, and advanced or metastatic breast cancer. The Company engaged in initiating the Phase II monotherapy and combination portions of this Phase I/II trial.

ZN-c3, an inhibitor of WEE1, a protein tyrosine kinase, is being evaluated in a Phase I/II clinical trial for the treatment of advanced solid tumors as a monotherapy and in a Phase Ib clinical trial in combination with chemotherapy in patients with advanced ovarian cancer. It uses its Integrated Discovery Engine to identify targets and develop small molecule chemical entities with properties.

Website

https://www.zentalis.com

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30 April 2022

Business

US stock market closes lower: Key indices down

After Friday trading The US stock market ended Friday's trading with decline amid negative dynamics...

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MALKOVICH John

I am humbled to be chosen for this award, which has been given to so many wonderful actors over the past 83 iterations of the Venice Film Festival

KIMMEL James

This is yet another attack on free speech, something that has become all too familiar for us at the show, for us in the country

COMPSTON Martin

It's for Jed to say, it's not for me to say whether the show will ever end but I think it's fair to say that this is the end of the story arc that's been building since series one. Everything will come to a head on this one.